Proton Pump Inhibitors & Dementia Artwork

Druggist For The People

Four score and seven minutes ago (about an hour and a half) your physician brought forth, upon her desk, a new prescription, conceived in best medical practice, and dedicated to the proposition that all generics are created equal. Now we are engaged in a great civilian war, testing whether that medication, or any medication so conceived, and so dedicated, can help us long endure. And maybe we can feel good at the same time. For forty years as a pharmacist, I've been building bridges - from the doctor to those in need of important drug information - you. With respect for the listener, and from the perspective that it is better to apply a recommended course of therapy than it is to comply with an ordered course, the goal here is not to provide specific answers about your drug therapy, but rather to help you generate the questions that will that will empower you in this. Toward that end, there will be weekly podcasts, very often with guests who will be "the people".

All Episodes

Druggist For The People

Proton Pump Inhibitors & Dementia

May 28, 2024 • Donald Schoeff R.Ph.

Send us a text

Summary: The Proton Pump Inhibitors (PPI’s), which include Prilosec, Prevacid, Protonix, Aciphex, and Nexium, are a very effective group of drugs to treat heartburn and reflux, but as with every other drug, there might be side effects and adverse effects, both short and long-term. In this episode, we discuss the possible link between the long-term use of PPI’s and dementia, as reported in the press and medical journals.

Topics:

· Proton Pump Inhibitors (PPI’s) 01:30

· H2 Blockers (Tagamet, Pepcid) 02:00

· Prevacid, Prilosec, Protonix, Nexium, Aciphex… 03:40

· Cause & Correlation 05:10

· Depression & Dementia (Correlation) 07:20

· How PPI’s Might Cause Dementia (MOA) 08:30

· Neurofibrillary Tangles and Amyloid Plaque 09:00

· Blood-Brain Barrier 09:45

· PPI’s & Decreased Vitamin B12 Absorption 11:00

· Benzo’s & PPI’s (Diazepam & Omeprazole) 12:00

· Participate in Care (Talk With Your Pharmacist) 13:30

· Medication Reconciliation 19:15

· Got a Question – Ask Your Doctor/Pharmacist 20:00

· Conflicting Study Results = We Don’t Know! 20:25

· Risk-Benefit 22:30

Questions and comments to druggistforthepeople@gmail.com

People on this episode

Donald J. Schoeff, R.Ph.

Host