Is My Generic Drug Actually Equivalent? Artwork

Druggist For The People

Four score and seven minutes ago (about an hour and a half) your physician brought forth, upon her desk, a new prescription, conceived in best medical practice, and dedicated to the proposition that all generics are created equal. Now we are engaged in a great civilian war, testing whether that medication, or any medication so conceived, and so dedicated, can help us long endure. And maybe we can feel good at the same time. For forty years as a pharmacist, I've been building bridges - from the doctor to those in need of important drug information - you. With respect for the listener, and from the perspective that it is better to apply a recommended course of therapy than it is to comply with an ordered course, the goal here is not to provide specific answers about your drug therapy, but rather to help you generate the questions that will that will empower you in this. Toward that end, there will be weekly podcasts, very often with guests who will be "the people".

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Druggist For The People

Is My Generic Drug Actually Equivalent?

June 18, 2024 • Donald Schoeff R.Ph.

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Summary: This episode discusses what makes a generic drug equivalent to a brand name drug, according to the FDA, and why some variability is okay - and unavoidable.
Also discussed is the importance of monitoring your response to the generic medication, use of Pill Identifiers, participating in the FDA Medwatch program, and utilizing your pharmacist for questions about generic substitutes, including the excipients that may be different from one manufacturer to another.

Topics:

· Changing Generic Companies 02:30

· Sertraline (Zoloft) 04:00

· Drug & Quantity Same 04:30

· Excipients Different 05:10

· Bioequivalence 05:30

· Pharmacokinetics 06:00

(Rate of absorption, Total Drug absorbed)

· Variance 07:00

· Statistics 08:00

· Confidence Interval 08:30

· Variance and Probability 12:30

· Monitor You! 13:45

· Pill Identifier 14:00

· MedWatch – FDA 14:40

· Excipients 16:00

Questions and comments to druggistforthepeople@gmail.com

People on this episode

Donald J. Schoeff, R.Ph.

Host